3PSD: Non-oxime pyrazole based inhibitors of B-Raf kinase

PDB ID: 3PSDDownload
MMDB ID: 90627
PDB Deposition Date: 2010/12/1
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 3.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3PSD: monomeric; determined by author and by software (PISA)
Molecular Components in 3PSD
Label Count Molecule
Protein (1 molecule)
1
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: BRAF)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
6-[1-(piperidin-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl]indeno[1,2-c]pyrazole6-[1-(piperidin-4-yl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl]indeno[1,2-c]pyrazole
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303