3PSB: Furo[2,3-c]pyridine-based Indanone Oximes as Potent and Selective B-Raf Inhibitors

PDB ID: 3PSBDownload
MMDB ID: 88115
PDB Deposition Date: 2010/12/1
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 3.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3PSB: monomeric; determined by author and by software (PISA)
Molecular Components in 3PSB
Label Count Molecule
Protein (1 molecule)
1
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: BRAF)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
ethyl 3-{[1-(hydroxyamino)-2H-inden-5-yl]amino}thieno[2,3-c]pyridine-2-carboxylateethyl 3-{[1-(hydroxyamino)-2H-inden-5-yl]amino}thieno[2,3-c]pyridine-2-carboxylate
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303