3PR0: Crystal Structure of a Covalently Bound alpha-Ketoheterocycle Inhibitor (Phenhexyl/Oxadiazole/Pyridine) to a Humanized Variant of Fatty Acid Amide Hydrolase

PDB ID: 3PR0Download
MMDB ID: 95035
PDB Deposition Date: 2010/11/29
Updated in MMDB: 2011/11
Experimental Method:
x-ray diffraction
Resolution: 2.2  Å
Source Organism:
Similar Structures:
Biological Unit for 3PR0: dimeric; determined by author and by software (PISA)
Molecular Components in 3PR0
Label Count Molecule
Proteins (2 molecules)
2
Fatty Acid Amide Hydrolase 1
(Gene symbol: Faah)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
2
7-phenyl-1-[5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl]heptane-1,1-diol7-phenyl-1-[5-(pyridin-2-yl)-1,3,4-oxadiazol-2-yl]heptane-1,1-diol
2
1
CHLORIDE IONCHLORIDE ION
3
2
DI(HYDROXYETHYL)ETHERDI(HYDROXYETHYL)ETHER
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303