3PFV: Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide

PDB ID: 3PFVDownload
MMDB ID: 87237
PDB Deposition Date: 2010/10/29
Updated in MMDB: 2023/12
Experimental Method:
x-ray diffraction
Resolution: 2.27  Å
Source Organism:
Similar Structures:
Biological Unit for 3PFV: dimeric; determined by software (PISA)
Molecular Components in 3PFV
Label Count Molecule
Proteins (2 molecules)
1
E3 Ubiquitin-protein Ligase Cbl-b
(Gene symbol: CBLB)
Molecule annotation
1
11-meric Peptide From Epidermal Growth Factor Receptor
(Gene symbol: EGFR)
Molecule annotation
Chemicals and Non-standard biopolymers (11 molecules)
1
1
SODIUM IONSODIUM ION
2
2
CHLORIDE IONCHLORIDE ION
3
5
SULFATE IONSULFATE ION
4
2
1,2-ETHANEDIOL1,2-ETHANEDIOL
5
1
TETRAETHYLENE GLYCOLTETRAETHYLENE GLYCOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303