3P6Z: Structural basis of thrombin mediated factor V activation: essential role of the hirudin-like sequence Glu666-Glu672 for processing at the heavy chain-B domain junction

PDB ID: 3P6ZDownload
MMDB ID: 91841
PDB Deposition Date: 2010/10/11
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3P6Z: trimeric; determined by author
Molecular Components in 3P6Z
Label Count Molecule
Proteins (3 molecules)
1
Thrombin Light Chain
(Gene symbol: F2)
Molecule annotation
1
Thrombin Heavy Chain
(Gene symbol: F2)
Molecule annotation
1
Coagulation Factor V
(Gene symbol: F5)
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
3
SODIUM IONSODIUM ION
2
1
D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamideD-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide
3
1
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
4
3
CHLORIDE IONCHLORIDE ION
5
1
(4S)-2-METHYL-2,4-PENTANEDIOL(4S)-2-METHYL-2,4-PENTANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303