3P3H: Human Carbonic Anhydrase Ii In Complex With P-(5-ferrocenyl-1h-1,2,3- Triazol-1-yl)benzenesulfonamide

Citation:
Abstract
We have determined the protein X-ray crystal structures of four organometallic inhibitors in complex with their target enzyme carbonic anhydrase II. The barrel-shaped hydrophobic ferrocene and ruthenocene moieties have provided a structure-based avenue to better occupy the hydrophobic binding patch within the enzyme active site.
PDB ID: 3P3HDownload
MMDB ID: 93872
PDB Deposition Date: 2010/10/4
Updated in MMDB: 2011/09
Experimental Method:
x-ray diffraction
Resolution: 1.5  Å
Source Organism:
Similar Structures:
Biological Unit for 3P3H: monomeric; determined by author and by software (PISA)
Molecular Components in 3P3H
Label Count Molecule
Protein (1 molecule)
1
Carbonic Anhydrase 2(Gene symbol: CA2)
Molecule annotation
Chemicals (3 molecules)
1
1
2
1
3
1
* Click molecule labels to explore molecular sequence information.

Citing MMDB
.