3OOF: Crystal structure of human FXR in complex with 4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid

PDB ID: 3OOFDownload
MMDB ID: 88077
PDB Deposition Date: 2010/8/31
Updated in MMDB: 2018/11
Experimental Method:
x-ray diffraction
Resolution: 2.29  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3OOF: dimeric; determined by author and by software (PISA)
Molecular Components in 3OOF
Label Count Molecule
Proteins (2 molecules)
1
Bile Acid Receptor
Molecule annotation
1
Peptide of Nuclear Receptor Coactivator 1
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid4-({(2S)-2-[2-(4-chlorophenyl)-5,6-difluoro-1H-benzimidazol-1-yl]-2-cyclohexylacetyl}amino)benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303