3OMJ: Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding

PDB ID: 3OMJDownload
MMDB ID: 84739
PDB Deposition Date: 2010/8/27
Updated in MMDB: 2010/10
Experimental Method:
x-ray diffraction
Resolution: 0.95  Å
Source Organism:
Biological Unit for 3OMJ: dimeric; determined by author and by software (PISA)
Molecular Components in 3OMJ
Label Count Molecule
Nucleotides(2 molecules)
2
5'-d(*cp*(c38)p*ap*gp*tp*ap*cp*tp*gp*g)-3'
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
4
CALCIUM IONCALCIUM ION
2
1
(23R,52R)-23,52-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,64-icosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10(65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone(23R,52R)-23,52-diamino-5,11,17,28,34,40,46,57-octamethyl-2,5,8,11,14,17,20,25,28,31,34,37,40,43,46,49,54,57,60,64-icosaazanonacyclo[54.2.1.1~4,7~.1~10,13~.1~16,19~.1~27,30~.1~33,36~.1~39,42~.1~45,48~]hexahexaconta-1(58),4(66),6,10(65),12,16(64),18,27(63),29,33(62),35,39(61),41,45(60),47,56(59)-hexadecaene-3,9,15,21,26,32,38,44,50,55-decone
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Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303