3O64: Crystal structure of catalytic domain of TACE with 2-(2-Aminothiazol-4-yl)pyrrolidine-Based Tartrate Diamides

PDB ID: 3O64Download
MMDB ID: 89997
PDB Deposition Date: 2010/7/28
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.88  Å
Source Organism:
Similar Structures:
Biological Unit for 3O64: monomeric; determined by author and by software (PISA)
Molecular Components in 3O64
Label Count Molecule
Protein (1 molecule)
1
Tace
(Gene symbol: ADAM17)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
ISOPROPYL ALCOHOLISOPROPYL ALCOHOL
2
1
N-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamideN-{(2R)-2-[2-(hydroxyamino)-2-oxoethyl]-4-methylpentanoyl}-3-methyl-L-valyl-N-(2-aminoethyl)-L-alaninamide
3
1
ZINC IONZINC ION
4
1
CALCIUM IONCALCIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303