3O1G: Cathepsin K covalently bound to a 2-cyano pyrimidine inhibitor with a benzyl P3 group

PDB ID: 3O1GDownload
MMDB ID: 85369
PDB Deposition Date: 2010/7/21
Updated in MMDB: 2010/11
Experimental Method:
x-ray diffraction
Resolution: 1.65  Å
Source Organism:
Similar Structures:
Biological Unit for 3O1G: monomeric; determined by author and by software (PISA)
Molecular Components in 3O1G
Label Count Molecule
Protein (1 molecule)
1
Cathepsin K
(Gene symbol: CTSK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
SULFATE IONSULFATE ION
2
1
N-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-[2-(dimethylamino)ethyl]-5-(trifluoromethyl)benzamideN-benzyl-3-(2-cyano-6-propylpyrimidin-4-yl)-N-[2-(dimethylamino)ethyl]-5-(trifluoromethyl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303