3O0U: Cathepsin K covalently bound to a cyano-pyrimidine inhibitor with improved selectivity over hERG

PDB ID: 3O0UDownload
MMDB ID: 89526
PDB Deposition Date: 2010/7/20
Updated in MMDB: 2011/05
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3O0U: monomeric; determined by author and by software (PISA)
Molecular Components in 3O0U
Label Count Molecule
Protein (1 molecule)
1
Cathepsin K
(Gene symbol: CTSK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
3-{2-[(E)-iminomethyl]-6-propylpyrimidin-4-yl}-N,N-dimethyl-5-(trifluoromethyl)benzamide3-{2-[(E)-iminomethyl]-6-propylpyrimidin-4-yl}-N,N-dimethyl-5-(trifluoromethyl)benzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303