3NRR: Co-crystal structure of dihydrofolate reductase-thymidylate synthase from Babesia bovis with dUMP, Raltitrexed and NADP

PDB ID: 3NRRDownload
MMDB ID: 83399
PDB Deposition Date: 2010/6/30
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3NRR: dimeric; determined by author and by software (PISA)
Molecular Components in 3NRR
Label Count Molecule
Proteins (2 molecules)
2
Dihydrofolate Reductase-thymidylate Synthase
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
2
CHLORIDE IONCHLORIDE ION
2
2
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
3
4
TOMUDEXTOMUDEX
4
2
2'-DEOXYURIDINE 5'-MONOPHOSPHATE2'-DEOXYURIDINE 5'-MONOPHOSPHATE
5
13
1,2-ETHANEDIOL1,2-ETHANEDIOL
6
1
GLYCEROLGLYCEROL
7
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303