3MJ1: X-ray crystal structure of ITK complexed with inhibitor RO5191614

PDB ID: 3MJ1Download
MMDB ID: 83075
PDB Deposition Date: 2010/4/12
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.72  Å
Source Organism:
Similar Structures:
Biological Unit for 3MJ1: monomeric; determined by author and by software (PISA)
Molecular Components in 3MJ1
Label Count Molecule
Protein (1 molecule)
1
Tyrosine-protein Kinase Itk/tsk
(Gene symbol: ITK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
7-[(4-methylpiperazin-1-yl)methyl]-4-[(3-methyl-1H-pyrazol-5-yl)amino]-2-(tetrahydro-2H-pyran-4-yl)phthalazin-1(2H)-one7-[(4-methylpiperazin-1-yl)methyl]-4-[(3-methyl-1H-pyrazol-5-yl)amino]-2-(tetrahydro-2H-pyran-4-yl)phthalazin-1(2H)-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303