3LAU: Crystal Structure of Aurora2 kinase in complex with a GSK3beta inhibitor

From an HTS hit, a series of potent and selective inhibitors of GSK3beta have been designed based on a Cdk2-homology model and with the help of several crystal structures of the compounds within Cdk2.
PDB ID: 3LAUDownload
MMDB ID: 80517
PDB Deposition Date: 2010/1/7
Updated in MMDB: 2011/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3LAU: monomeric; determined by author and by software (PISA)
Molecular Components in 3LAU
Label Count Molecule
Protein (1 molecule)
Serine/threonine-protein Kinase 6(Gene symbol: AURKA)
Molecule annotation
Chemical (1 molecule)
* Click molecule labels to explore molecular sequence information.

Citing MMDB