3L8P: Crystal structure of cytoplasmic kinase domain of Tie2 complexed with inhibitor CEP11207

PDB ID: 3L8PDownload
MMDB ID: 85326
PDB Deposition Date: 2010/1/3
Updated in MMDB: 2010/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3L8P: monomeric; determined by author and by software (PISA)
Molecular Components in 3L8P
Label Count Molecule
Protein (1 molecule)
1
Angiopoietin-1 Receptor
(Gene symbol: TEK)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
2-methyl-11-(1-methylethyl)-8-[(2S)-tetrahydro-2H-pyran-2-yl]-2,11,12,13-tetrahydro-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one2-methyl-11-(1-methylethyl)-8-[(2S)-tetrahydro-2H-pyran-2-yl]-2,11,12,13-tetrahydro-4H-indazolo[5,4-a]pyrrolo[3,4-c]carbazol-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303