3L1S: 3-Aryl-4-(arylhydrazono)-1H-pyrazol-5-ones: Highly ligand efficient and potent inhibitors of GSK3

PDB ID: 3L1SDownload
MMDB ID: 80508
PDB Deposition Date: 2009/12/14
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3L1S: monomeric; determined by author and by software (PISA)
Molecular Components in 3L1S
Label Count Molecule
Protein (1 molecule)
1
Glycogen Synthase Kinase-3 Beta
(Gene symbol: GSK3B)
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
(4E)-4-[(4-chlorophenyl)hydrazono]-5-(3,4-dimethoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one(4E)-4-[(4-chlorophenyl)hydrazono]-5-(3,4-dimethoxyphenyl)-2,4-dihydro-3H-pyrazol-3-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303