3KWZ: Cathepsin K in complex with a non-selective 2-cyano-pyrimidine inhibitor

PDB ID: 3KWZDownload
MMDB ID: 80498
PDB Deposition Date: 2009/12/2
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.49  Å
Source Organism:
Similar Structures:
Biological Unit for 3KWZ: monomeric; determined by author and by software (PISA)
Molecular Components in 3KWZ
Label Count Molecule
Protein (1 molecule)
1
Cathepsin K
(Gene symbol: CTSK)
Molecule annotation
Chemicals and Non-standard biopolymers (7 molecules)
1
6
SULFATE IONSULFATE ION
2
1
4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile4-(3-piperidin-1-ylpropyl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-2-carbonitrile
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303