3KVK: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with amino-benzoic acid inhibitor 641 at 2.05A resolution

PDB ID: 3KVKDownload
MMDB ID: 80494
PDB Deposition Date: 2009/11/30
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 3KVK: monomeric; determined by author and by software (PISA)
Molecular Components in 3KVK
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase, Mitochondrial
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
SULFATE IONSULFATE ION
2
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
1
(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID(4S)-2,6-DIOXOHEXAHYDROPYRIMIDINE-4-CARBOXYLIC ACID
4
1
UNDECYLAMINE-N,N-DIMETHYL-N-OXIDEUNDECYLAMINE-N,N-DIMETHYL-N-OXIDE
5
1
2-{[(3,5-dichlorophenyl)carbamoyl]amino}benzoic acid2-{[(3,5-dichlorophenyl)carbamoyl]amino}benzoic acid
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303