3KRK: X-ray crystal structure of arachidonic acid bound in the cyclooxygenase channel of L531F murine COX-2

PDB ID: 3KRKDownload
MMDB ID: 81988
PDB Deposition Date: 2009/11/18
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3KRK: dimeric; determined by author and by software (PISA)
Molecular Components in 3KRK
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: Ptgs2)
Molecule annotation
Chemicals and Non-standard biopolymers (24 molecules)
1
10
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-D-mannopyranosealpha-D-mannopyranose
3
2
ARACHIDONIC ACIDARACHIDONIC ACID
4
4
ACRYLIC ACIDACRYLIC ACID
5
3
GLYCEROLGLYCEROL
6
2
PROTOPORPHYRIN IX CONTAINING COPROTOPORPHYRIN IX CONTAINING CO
7
2
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303