3KR8: Human tankyrase 2 - catalytic PARP domain in complex with an inhibitor XAV939

PDB ID: 3KR8Download
MMDB ID: 78796
PDB Deposition Date: 2009/11/18
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3KR8: monomeric; determined by author and by software (PISA)
Molecular Components in 3KR8
Label Count Molecule
Protein (1 molecule)
1
Tankyrase-2
(Gene symbol: TNKS2)
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
ZINC IONZINC ION
2
1
2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol2-[4-(trifluoromethyl)phenyl]-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-4-ol
3
2
SULFATE IONSULFATE ION
4
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303