3KLF: Crystal structure of wild-type HIV-1 Reverse Transcriptase crosslinked to a DSDNA with a bound excision product, AZTPPPPA

PDB ID: 3KLFDownload
MMDB ID: 85000
PDB Deposition Date: 2009/11/7
Updated in MMDB: 2024/10
Experimental Method:
x-ray diffraction
Resolution: 3.15  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3KLF: tetrameric; determined by author and by software (PISA)
Molecular Components in 3KLF
Label Count Molecule
Proteins (2 molecules)
1
Reverse Transcriptase/ribonuclease H
Molecule annotation
1
P51 RT
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*ap*t*gp*cp*ap*tp*gp*gp*cp*gp*cp*cp*cp*gp*ap*ap*cp*ap*gp*gp*gp*ap*cp*tp*gp*tp*g)-3')
Molecule annotation
1
DNA (5'-d(*a*cp*ap*gp*tp*cp*cp*cp*tp*gp*tp*tp*cp*gp*gp*(mrg)p*cp*gp*cp*cp*(2da))-3')
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
MAGNESIUM IONMAGNESIUM ION
2
1
[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl] [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl hydrogen phosphate[[[[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl] [(2S,3S,5R)-3-azido-5-(5-methyl-2,4-dioxo-pyrimidin-1-yl)oxolan-2-yl]methyl hydrogen phosphate
3
1
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303