3K83: Crystal Structure Analysis of a Biphenyl/Oxazole/Carboxypyridine alpha-ketoheterocycle Inhibitor Bound to a Humanized Variant of Fatty Acid Amide Hydrolase

PDB ID: 3K83Download
MMDB ID: 78453
PDB Deposition Date: 2009/10/13
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 2.251  Å
Source Organism:
Similar Structures:
Biological Unit for 3K83: dimeric; determined by author and by software (PISA)
Molecular Components in 3K83
Label Count Molecule
Proteins (2 molecules)
2
Fatty-acid Amide Hydrolase 1
(Gene symbol: Faah)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
2
6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid6-[2-(3-biphenyl-4-ylpropanoyl)-1,3-oxazol-5-yl]pyridine-2-carboxylic acid
2
1
CHLORIDE IONCHLORIDE ION
3
1
1-DODECANOL1-DODECANOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303