3K3H: Crystal structure of the PDE9A catalytic domain in complex with (S)-BAY73-6691

PDB ID: 3K3HDownload
MMDB ID: 80130
PDB Deposition Date: 2009/10/2
Updated in MMDB: 2013/11
Experimental Method:
x-ray diffraction
Resolution: 2.5  Å
Source Organism:
Similar Structures:
Biological Unit for 3K3H: dimeric; determined by software (PISA)
Molecular Components in 3K3H
Label Count Molecule
Proteins (2 molecules)
2
High Affinity Cgmp-specific 3',5'-cyclic Phosphodiesterase 9A
(Gene symbol: PDE9A)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
2
ZINC IONZINC ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
1-(2-chlorophenyl)-6-[(2S)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one1-(2-chlorophenyl)-6-[(2S)-3,3,3-trifluoro-2-methylpropyl]-1,7-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303