3JSM: K65R mutant HIV-1 reverse transcriptase cross-linked to DS-DNA and complexed with tenofovir-diphosphate as the incoming nucleotide substrate

PDB ID: 3JSMDownload
MMDB ID: 77081
PDB Deposition Date: 2009/9/10
Updated in MMDB: 2009/12
Experimental Method:
x-ray diffraction
Resolution: 3  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3JSM: tetrameric; determined by author and by software (PISA)
Molecular Components in 3JSM
Label Count Molecule
Proteins (2 molecules)
1
Hiv-1 Reverse Transcriptase P66 Subunit
Molecule annotation
1
Hiv-1 Reverse Transcriptase P51 Subunit
Molecule annotation
Nucleotides(2 molecules)
1
DNA (5'-d(*a*tp*gp*gp*tp*cp*gp*gp*cp*gp*cp*cp*cp*gp*ap*ap*cp*ap*gp*gp*gp*ap*cp*tp*gp*tp*g)-3')
Molecule annotation
1
DNA (5'-d(*a*cp*ap*gp*tp*cp*cp*cp*tp*gp*tp*tp*cp*gp*gp*(mrg)p*cp*gp*cp*cp*(ddg))-3')
Molecule annotation
Chemicals and Non-standard biopolymers (5 molecules)
1
1
[2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY]METHYL-TRIPHOSPHATE[2-(6-AMINO-9H-PURIN-9-YL)-1-METHYLETHOXY]METHYL-TRIPHOSPHATE
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303