3JQF: Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 1,3,5-triazine-2,4,6-triamine (AX2)

PDB ID: 3JQFDownload
MMDB ID: 78616
PDB Deposition Date: 2009/9/6
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3JQF: tetrameric; determined by author and by software (PISA)
Molecular Components in 3JQF
Label Count Molecule
Proteins (4 molecules)
3
Pteridine Reductase 1
Molecule annotation
1
Pteridine Reductase 1
Molecule annotation
Chemicals and Non-standard biopolymers (25 molecules)
1
4
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
4
1,3,5-triazine-2,4,6-triamine1,3,5-triazine-2,4,6-triamine
3
5
2,3-DIHYDROXY-1,4-DITHIOBUTANE2,3-DIHYDROXY-1,4-DITHIOBUTANE
4
4
(4S,5S)-1,2-DITHIANE-4,5-DIOL(4S,5S)-1,2-DITHIANE-4,5-DIOL
5
6
ACETATE IONACETATE ION
6
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303