3IIT: Factor XA in complex with a cis-1,2-diaminocyclohexane derivative

PDB ID: 3IITDownload
MMDB ID: 83810
PDB Deposition Date: 2009/8/3
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3IIT: dimeric; determined by author and by software (PISA)
Molecular Components in 3IIT
Label Count Molecule
Proteins (2 molecules)
1
Activated Factor XA Heavy Chain
(Gene symbol: F10)
Molecule annotation
1
Factor X Light Chain
(Gene symbol: F10)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
CALCIUM IONCALCIUM ION
2
1
7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide7-chloro-N-[(1S,2R,4S)-4-(dimethylcarbamoyl)-2-{[(5-methyl-5,6-dihydro-4H-pyrrolo[3,4-d][1,3]thiazol-2-yl)carbonyl]amino}cyclohexyl]isoquinoline-3-carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303