3II5: The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor

PDB ID: 3II5Download
MMDB ID: 78017
PDB Deposition Date: 2009/7/31
Updated in MMDB: 2009/11
Experimental Method:
x-ray diffraction
Resolution: 2.79  Å
Source Organism:
Similar Structures:
Biological Unit for 3II5: monomeric; determined by author
Molecular Components in 3II5
Label Count Molecule
Protein (1 molecule)
1
B-raf Proto-oncogene Serine/threonine-protein Kinase
(Gene symbol: BRAF)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
N-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamideN-[3-(3-{4-[(dimethylamino)methyl]phenyl}pyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-3-(trifluoromethyl)benzamide
2
2
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303