3IA4: Moritella profunda dihydrofolate reductase (DHFR) in complex with NADPH and methotrexate (MTX)

PDB ID: 3IA4Download
MMDB ID: 75522
PDB Deposition Date: 2009/7/13
Updated in MMDB: 2009/09
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
Similar Structures:
Biological Unit for 3IA4: monomeric; determined by author and by software (PISA)
Molecular Components in 3IA4
Label Count Molecule
Protein (1 molecule)
1
Dihydrofolate Reductase
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATENADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
METHOTREXATEMETHOTREXATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303