3HY4: Structure of human MTHFS with N5-iminium phosphate

PDB ID: 3HY4Download
MMDB ID: 75347
PDB Deposition Date: 2009/6/22
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.795  Å
Source Organism:
Similar Structures:
Biological Unit for 3HY4: monomeric; determined by author and by software (PISA)
Molecular Components in 3HY4
Label Count Molecule
Protein (1 molecule)
1
5-formyltetrahydrofolate Cyclo-ligase
(Gene symbol: MTHFS)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
NICKEL (II) IONNICKEL (II) ION
2
3
MAGNESIUM IONMAGNESIUM ION
3
1
N-({trans-4-[({(2R,4R,4aS,6S,8aS)-2-amino-4-hydroxy-5-[(phosphonooxy)methyl]decahydropteridin-6-yl}methyl)amino]cyclohexyl}carbonyl)-L-glutamic acidN-({trans-4-[({(2R,4R,4aS,6S,8aS)-2-amino-4-hydroxy-5-[(phosphonooxy)methyl]decahydropteridin-6-yl}methyl)amino]cyclohexyl}carbonyl)-L-glutamic acid
4
1
PHOSPHATE IONPHOSPHATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303