3HS6: X-ray crystal structure of eicosapentaenoic acid bound to the cyclooxygenase channel of cyclooxygenase-2

PDB ID: 3HS6Download
MMDB ID: 81968
PDB Deposition Date: 2009/6/10
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 2.4  Å
Source Organism:
Similar Structures:
Biological Unit for 3HS6: dimeric; determined by author and by software (PISA)
Molecular Components in 3HS6
Label Count Molecule
Proteins (2 molecules)
2
Prostaglandin G/H Synthase 2
(Gene symbol: Ptgs2)
Molecule annotation
Chemicals and Non-standard biopolymers (29 molecules)
1
9
2-acetamido-2-deoxy-beta-D-glucopyranose2-acetamido-2-deoxy-beta-D-glucopyranose
2
1
alpha-D-mannopyranosealpha-D-mannopyranose
3
1
2-acetamido-2-deoxy-alpha-D-glucopyranose2-acetamido-2-deoxy-alpha-D-glucopyranose
4
2
5,8,11,14,17-EICOSAPENTAENOIC ACID5,8,11,14,17-EICOSAPENTAENOIC ACID
5
4
ACRYLIC ACIDACRYLIC ACID
6
2
PROTOPORPHYRIN IX CONTAINING COPROTOPORPHYRIN IX CONTAINING CO
7
2
octyl beta-D-glucopyranosideoctyl beta-D-glucopyranoside
8
8
1,2-ETHANEDIOL1,2-ETHANEDIOL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303