3HDZ: Identification, Synthesis, and SAR of Amino Substituted Pyrido[3,2b]pryaziones as Potent and Selective PDE5 Inhibitors

PDB ID: 3HDZDownload
MMDB ID: 75172
PDB Deposition Date: 2009/5/7
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3HDZ: monomeric; determined by author and by software (PISA)
Molecular Components in 3HDZ
Label Count Molecule
Protein (1 molecule)
Cgmp-specific 3',5'-cyclic Phosphodiesterase,camp-specific 3',5'-cyclic Phosphodiesterase 4a,cgmp-specific 3',5'-cyclic Phosphodiesterase
(Gene symbol: PDE5A)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
* Click molecule labels to explore molecular sequence information.

Citing MMDB