3HA6: Crystal Structure Of Aurora A In Complex With Tpx2 And Compound 10

PDB ID: 3HA6Download
MMDB ID: 75802
PDB Deposition Date: 2009/5/1
Updated in MMDB: 2010/09
Experimental Method:
x-ray diffraction
Resolution: 2.36  Å
Source Organism:
Similar Structures:
Biological Unit for 3HA6: tetrameric; determined by software (PISA)
Molecular Components in 3HA6
Label Count Molecule
Proteins (4 molecules)
2
Serine/threonine-protein Kinase 6
(Gene symbol: AURKA)
Molecule annotation
2
Targeting Protein for Xklp2
(Gene symbol: TPX2)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
N~2~-(3,4-dimethoxyphenyl)-n~4~-[2-(2-fluorophenyl)ethyl]-n~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamineN~2~-(3,4-dimethoxyphenyl)-n~4~-[2-(2-fluorophenyl)ethyl]-n~6~-quinolin-6-yl-1,3,5-triazine-2,4,6-triamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303