3H9F: Crystal Structure Of Human Dual Specificity Protein Kinase (Ttk) In Complex With A Pyrimido-Diazepin Ligand

PDB ID: 3H9FDownload
MMDB ID: 72820
PDB Deposition Date: 2009/4/30
Updated in MMDB: 2012/11
Experimental Method:
x-ray diffraction
Resolution: 2.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3H9F: monomeric; determined by author
Molecular Components in 3H9F
Label Count Molecule
Protein (1 molecule)
1
Dual Specificity Protein Kinase TTK
(Gene symbol: TTK)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
2
Magnesium IonMagnesium Ion
2
1
9-Cyclopentyl-2-(4-(4-Hydroxypiperidin-1-Yl)-2-Methoxyphenylamino)-5-Methyl-8,9-Dihydro-5h-Pyrimido[4,5-B][1,4]diazepin-6(7h)-One9-cyclopentyl-2-{[4-(4-hydroxypiperidin-1-yl)-2-methoxyphenyl]amino}-5-methyl-5,7,8,9-tetrahydro-6h-pyrimido[4,5-b][1,4]diazepin-6-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303