3H6O: Activator-Bound Structure of Human Pyruvate Kinase M2

PDB ID: 3H6ODownload
MMDB ID: 72528
PDB Deposition Date: 2009/4/23
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3H6O: tetrameric; determined by software (PISA)
Molecular Components in 3H6O
Label Count Molecule
Proteins (4 molecules)
4
Pyruvate Kinase Isozymes M1/m2
(Gene symbol: PKM)
Molecule annotation
Chemicals and Non-standard biopolymers (37 molecules)
1
4
BETA-FRUCTOSE-1,6-DIPHOSPHATEBETA-FRUCTOSE-1,6-DIPHOSPHATE
2
31
Molecule information is not available.
3
2
6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one6-(2-fluorobenzyl)-2,4-dimethyl-4,6-dihydro-5H-thieno[2',3':4,5]pyrrolo[2,3-d]pyridazin-5-one
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303