3H42: Crystal structure of PCSK9 in complex with Fab from LDLR competitive antibody

PDB ID: 3H42Download
MMDB ID: 72514
PDB Deposition Date: 2009/4/17
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.3  Å
Source Organism:
Similar Structures:
Biological Unit for 3H42: tetrameric; determined by software (PISA)
Molecular Components in 3H42
Label Count Molecule
Proteins (4 molecules)
1
Proprotein Convertase Subtilisin/kexin Type 9
(Gene symbol: PCSK9)
Molecule annotation
1
Proprotein Convertase Subtilisin/kexin Type 9
(Gene symbol: PCSK9)
Molecule annotation
1
FAB From Ldlr Competitive Antibody: Light Chain
Molecule annotation
1
FAB From Ldlr Competitive Antibody: Heavy Chain
Molecule annotation
Chemical and Non-standard biopolymers (1 molecule)
1
1
SODIUM IONSODIUM ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303