3H0E: 3,4-Dihydropyrimido(1,2-A)indol-10(2h)-Ones As Potent Non- Peptidic Inhibitors Of Caspase-3

PDB ID: 3H0EDownload
MMDB ID: 78163
PDB Deposition Date: 2009/4/9
Updated in MMDB: 2009/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3H0E: dimeric; determined by author and by software (PISA)
Molecular Components in 3H0E
Label Count Molecule
Proteins (2 molecules)
2
Caspase-3
(Gene symbol: CASP3)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
2
(10s)-3,3-dimethyl-8-{[(2s)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl}-2,3,4,10-tetrahydropyrimido[1,2-a]indol-10-ol(10s)-3,3-dimethyl-8-{[(2s)-2-(phenoxymethyl)pyrrolidin-1-yl]sulfonyl}-2,3,4,10-tetrahydropyrimido[1,2-a]indol-10-ol
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303