3GR4: Activator-Bound Structure of Human Pyruvate Kinase M2

PDB ID: 3GR4Download
MMDB ID: 70740
PDB Deposition Date: 2009/3/24
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.6  Å
Source Organism:
Similar Structures:
Biological Unit for 3GR4: tetrameric; determined by software (PISA)
Molecular Components in 3GR4
Label Count Molecule
Proteins (4 molecules)
4
Pyruvate Kinase Isozymes M1/m2
(Gene symbol: PKM)
Molecule annotation
Chemicals and Non-standard biopolymers (32 molecules)
1
4
1,6-di-O-phosphono-beta-D-fructofuranose1,6-di-O-phosphono-beta-D-fructofuranose
2
7
L(+)-TARTARIC ACIDL(+)-TARTARIC ACID
3
2
1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine1-[(2,6-difluorophenyl)sulfonyl]-4-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)piperazine
4
18
Molecule information is not available.
5
1
ADENOSINE-5'-DIPHOSPHATEADENOSINE-5'-DIPHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303