3GNW: HCV NS5B polymerase in complex with 1,5 benzodiazepine inhibitor 4c

PDB ID: 3GNWDownload
MMDB ID: 77487
PDB Deposition Date: 2009/3/18
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2.39  Å
Source Organism:
Similar Structures:
Biological Unit for 3GNW: monomeric; determined by author and by software (PISA)
Molecular Components in 3GNW
Label Count Molecule
Protein (1 molecule)
1
RNA-directed RNA Polymerase
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
(11S)-11-[4-(benzyloxy)-2-fluorophenyl]-3,3-dimethyl-10-[(6-methylpyridin-2-yl)carbonyl]-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide(11S)-11-[4-(benzyloxy)-2-fluorophenyl]-3,3-dimethyl-10-[(6-methylpyridin-2-yl)carbonyl]-2,3,4,5,10,11-hexahydrothiopyrano[3,2-b][1,5]benzodiazepin-6-ol 1,1-dioxide
2
2
CHLORIDE IONCHLORIDE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303