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3GHU:
Human aldose reductase in complex with NADP+ and the inhibitor IDD594. Investigation of global effects of radiation damage on protein structure. Forth stage of radiation damage
PDB ID:
3GHU
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MMDB ID:
70462
PDB Deposition Date:
2009/3/4
Updated in MMDB:
2023/09
Experimental Method:
x-ray diffraction
Resolution:
1.2 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3GHU: monomeric; determined by author and by software (PISA)
Molecular Components in 3GHU
Label
Count
Molecule
Protein (1 molecule)
A
1
Aldose Reductase
(Gene symbol:
AKR1B1
)
Chemicals and Non-standard biopolymers (3 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
IDD594
3
1
CITRIC ACID
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303