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3GFE:
Crystal Structure Of P38a Mitogen-Activated Protein Kinase In Complex With A Pyrazolopyridinone Inhibitor
PDB ID:
3GFE
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MMDB ID:
75312
PDB Deposition Date:
2009/2/26
Updated in MMDB:
2009/08
Experimental Method:
x-ray diffraction
Resolution:
2.1 Å
Source Organism:
Homo sapiens
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3GFE: monomeric; determined by author and by software (PISA)
Molecular Components in 3GFE
Label
Count
Molecule
Protein (1 molecule)
A
1
Mitogen-activated Protein Kinase 14
(Gene symbol:
MAPK14
)
Chemical and Non-standard biopolymers (1 molecule)
1
1
N-cyclopropyl-3-{[1-(2,4-difluorophenyl)-7-methyl-6-oxo-6,7-dihydro-1h-pyrazolo[3,4-b]pyridin-4-yl]amino}-4-methylbenzamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303