3GC9: The structure of p38beta C119S, C162S in complex with a dihydroquinazolinone inhibitor

PDB ID: 3GC9Download
MMDB ID: 75451
PDB Deposition Date: 2009/2/21
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.05  Å
Source Organism:
Similar Structures:
Biological Unit for 3GC9: monomeric; determined by author and by software (PISA)
Molecular Components in 3GC9
Label Count Molecule
Protein (1 molecule)
1
Mitogen-activated Protein Kinase 11
(Gene symbol: MAPK11)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
SODIUM IONSODIUM ION
2
1
5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1H)-one5-(2-chloro-4-fluorophenyl)-1-(2,6-dichlorophenyl)-7-[1-(1-methylethyl)piperidin-4-yl]-3,4-dihydroquinazolin-2(1H)-one
3
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303