3G72: Design And Preparation Of Potent, Non-Peptidic, Bioavailable Renin Inhibitors

PDB ID: 3G72Download
MMDB ID: 74971
PDB Deposition Date: 2009/2/9
Updated in MMDB: 2012/12
Experimental Method:
x-ray diffraction
Resolution: 1.9  Å
Source Organism:
Similar Structures:
Biological Unit for 3G72: monomeric; determined by author
Molecular Components in 3G72
Label Count Molecule
Protein (1 molecule)
1
Renin
(Gene symbol: REN)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
Dimethyl SulfoxideDimethyl Sulfoxide
2
1
N-Acetyl-D-GlucosamineN-Acetyl-D-Glucosamine
3
1
(1s,5r)-7-{4-[3-(2-Chloro-3,6-Difluorophenoxy)propyl]phenyl}-N-Cyclopropyl-N-(2,3-Dichlorobenzyl)-3,9-Diazabicyclo[3.3.1]non-6-Ene-6-Carboxamide(1s,5r)-7-{4-[3-(2-Chloro-3,6-Difluorophenoxy)propyl]phenyl}-N-Cyclopropyl-N-(2,3-Dichlorobenzyl)-3,9-Diazabicyclo[3.3.1]non-6-Ene-6-Carboxamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303