3G5M: Synthesis of Casimiroin and Optimization of Its Quinone Reductase 2 and Aromatase Inhibitory activity

PDB ID: 3G5MDownload
MMDB ID: 70430
PDB Deposition Date: 2009/2/5
Updated in MMDB: 2023/09
Experimental Method:
x-ray diffraction
Resolution: 1.84  Å
Source Organism:
Similar Structures:
Biological Unit for 3G5M: dimeric; determined by author and by software (PISA)
Molecular Components in 3G5M
Label Count Molecule
Proteins (2 molecules)
2
Ribosyldihydronicotinamide Dehydrogenase [quinone]
(Gene symbol: NQO2)
Molecule annotation
Chemicals and Non-standard biopolymers (8 molecules)
1
2
ZINC IONZINC ION
2
4
6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one6-methoxy-9-methyl[1,3]dioxolo[4,5-h]quinolin-8(9H)-one
3
2
FLAVIN-ADENINE DINUCLEOTIDEFLAVIN-ADENINE DINUCLEOTIDE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303