3G42: Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor

PDB ID: 3G42Download
MMDB ID: 72783
PDB Deposition Date: 2009/2/3
Updated in MMDB: 2021/10
Experimental Method:
x-ray diffraction
Resolution: 2.1  Å
Source Organism:
Similar Structures:
Biological Unit for 3G42: monomeric; determined by author and by software (PISA)
Molecular Components in 3G42
Label Count Molecule
Protein (1 molecule)
1
Adam 17
(Gene symbol: ADAM17)
Molecule annotation
Chemicals and Non-standard biopolymers (2 molecules)
1
1
N-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophanN-{[4-(but-2-yn-1-yloxy)phenyl]sulfonyl}-5-methyl-D-tryptophan
2
1
ZINC IONZINC ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303