3G0X: Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 5

PDB ID: 3G0XDownload
MMDB ID: 73162
PDB Deposition Date: 2009/1/29
Updated in MMDB: 2009/06
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3G0X: monomeric; determined by author and by software (PISA)
Molecular Components in 3G0X
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (4 molecules)
1
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
2
1
OROTIC ACIDOROTIC ACID
3
1
(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide(2Z)-N-biphenyl-4-yl-2-cyano-3-cyclopropyl-3-hydroxyprop-2-enamide
4
1
SULFATE IONSULFATE ION
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303