3G0U: Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 4

PDB ID: 3G0UDownload
MMDB ID: 73161
PDB Deposition Date: 2009/1/28
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 2  Å
Source Organism:
Similar Structures:
Biological Unit for 3G0U: monomeric; determined by author and by software (PISA)
Molecular Components in 3G0U
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (3 molecules)
1
1
OROTIC ACIDOROTIC ACID
2
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
1
(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide(2Z)-N-(3-chloro-2'-methoxybiphenyl-4-yl)-2-cyano-3-hydroxybut-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303