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3FQZ:
Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(3-methoxy-4-phenylphenyl)but-1-ynyl]-6-methylpyrimidine
PDB ID:
3FQZ
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MMDB ID:
70407
PDB Deposition Date:
2009/1/7
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
1.72 Å
Source Organism:
Staphylococcus aureus RF122
Similar Structures:
VAST+
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Biological Unit for 3FQZ: monomeric; determined by author and by software (PISA)
Molecular Components in 3FQZ
Label
Count
Molecule
Protein (1 molecule)
A
1
Trimethoprim-sensitive Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
5-[(3S)-3-(2-methoxybiphenyl-4-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
2
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303