3FQX: Phosphorylation of self-peptides alters Human Leukocyte Antigen Class I-restricted antigen presentation and generates tumor specific epitopes

PDB ID: 3FQXDownload
MMDB ID: 69995
PDB Deposition Date: 2009/1/7
Updated in MMDB: 2017/11
Experimental Method:
x-ray diffraction
Resolution: 1.7  Å
Source Organism:
synthetic construct▼
Similar Structures:
Biological Unit for 3FQX: trimeric; determined by author and by software (PISA)
Molecular Components in 3FQX
Label Count Molecule
Proteins (3 molecules)
1
HLA Class I Histocompatibility Antigen, A-2 Alpha Chain
Molecule annotation
1
Beta-2-microglobulin
Molecule annotation
1
Phospho-peptide 1097-1105 From Insulin Receptor Substrate 2 (Irs2): Rva(sep)ptsgv
Molecule annotation
Chemicals and Non-standard biopolymers (9 molecules)
1
5
CADMIUM IONCADMIUM ION
2
2
MAGNESIUM IONMAGNESIUM ION
3
2
GLYCEROLGLYCEROL
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303