NCBI
National Center for
Biotechnology Information
Search
3FQO:
Staphylococcus aureus F98Y mutant dihydrofolate reductase complexed with NADPH and 2,4-diamino-5-[3-(2,5-dimethoxyphenyl)prop-1-ynyl]-6-ethylpyrimidine (UCP120B)
PDB ID:
3FQO
Download
MMDB ID:
70404
PDB Deposition Date:
2009/1/7
Updated in MMDB:
2017/11
Experimental Method:
x-ray diffraction
Resolution:
2.09 Å
Source Organism:
Staphylococcus aureus RF122
Similar Structures:
VAST+
Download sequence data
Biological Unit for 3FQO: monomeric; determined by author and by software (PISA)
Molecular Components in 3FQO
Label
Count
Molecule
Protein (1 molecule)
A
1
Trimethoprim-sensitive Dihydrofolate Reductase
Chemicals and Non-standard biopolymers (2 molecules)
1
1
NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
2
1
5-[3-(2,5-dimethoxyphenyl)prop-1-yn-1-yl]-6-ethylpyrimidine-2,4-diamine
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH.
"
MMDB and VAST+: tracking structural similarities between macromolecular complexes.
Nucleic Acids Res. 2014 Jan; 42(Database issue)
:D297-303