3FJ6: Human dihydroorotate dehydrogenase in complex with a leflunomide derivative inhibitor 2

PDB ID: 3FJ6Download
MMDB ID: 73152
PDB Deposition Date: 2008/12/14
Updated in MMDB: 2023/11
Experimental Method:
x-ray diffraction
Resolution: 1.8  Å
Source Organism:
Similar Structures:
Biological Unit for 3FJ6: monomeric; determined by author and by software (PISA)
Molecular Components in 3FJ6
Label Count Molecule
Protein (1 molecule)
1
Dihydroorotate Dehydrogenase
(Gene symbol: DHODH)
Molecule annotation
Chemicals and Non-standard biopolymers (6 molecules)
1
1
OROTIC ACIDOROTIC ACID
2
1
FLAVIN MONONUCLEOTIDEFLAVIN MONONUCLEOTIDE
3
1
SULFATE IONSULFATE ION
4
2
ACETATE IONACETATE ION
5
1
(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide(2Z)-2-cyano-N-(2,2'-dichlorobiphenyl-4-yl)-3-hydroxybut-2-enamide
* Click molecule labels to explore molecular sequence information.
Citing MMDB
Madej T, Lanczycki CJ, Zhang D, Thiessen PA, Geer RC, Marchler-Bauer A, Bryant SH. " MMDB and VAST+: tracking structural similarities between macromolecular complexes. Nucleic Acids Res. 2014 Jan; 42(Database issue):D297-303